Which symptoms are characteristic of adult-onset Still's disease?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Adult-onset Still's disease is characterized by a triad of symptoms: high fevers, arthritis, and a distinctive salmon-colored rash. These symptoms reflect the systemic inflammatory nature of the disease.

The fever typically presents in quotidian patterns, often spiking in the afternoon or evening, and can be accompanied by sweating. The rash is notable for its transient appearance, often accompanying fever episodes and generally resolves as the fever subsides. Joint pain or arthralgias is another common feature, typically affecting large joints like the knees and wrists.

Combining these elements, option C captures the essence of adult-onset Still's disease with arthralgias (joint pain), rash, and fever as key indicators of this condition. Each of these symptoms plays a critical role in guiding diagnosis and emphasizing the systemic nature of the disease, which is often confused with other rheumatological and infectious conditions.

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