Which symptom is NOT associated with lithium toxicity?

In assessing the symptoms associated with lithium toxicity, it is important to recognize that the main features include neurological and gastrointestinal manifestations. Ataxia, nausea, and tremors are all common symptoms that can arise due to elevated lithium levels in the body.

Ataxia, which refers to a lack of coordination and unsteady movements, occurs because lithium affects the central nervous system, particularly the cerebellum. Nausea, often experienced as an early symptom of lithium toxicity, highlights its gastrointestinal side effects. Tremors, another classic sign, represent a neuromuscular instability resulting from lithium's effects on neuronal excitability.

In contrast, hypertension is not a typical manifestation of lithium toxicity. While lithium can affect renal function and electrolyte balance, leading potentially to other complications, hypertension is not directly linked as a symptom of acute lithium toxicity. Instead, patients might experience hypotension or a lack of blood pressure changes related to its side effects. Understanding these associations helps in monitoring and managing patients on lithium therapy, particularly when signs of toxicity arise.