Which of the following is commonly associated with nephrotic syndrome and indicates an increased risk for cardiovascular events?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

The association of dyslipidemia with nephrotic syndrome is significant due to the alterations in lipid metabolism that occur as a result of the loss of proteins in the urine. Nephrotic syndrome leads to a substantial decrease in serum albumin levels, which in turn stimulates the liver to increase the production of lipoproteins, including cholesterol and triglycerides. This results in dyslipidemia, characterized by elevated levels of low-density lipoprotein (LDL) cholesterol and triglycerides.

Patients with dyslipidemia, particularly those with elevated triglycerides, have a higher risk of cardiovascular events. This increased risk is attributed to the accumulation of lipids in the bloodstream, which can lead to atherosclerosis, hypertension, and other cardiovascular complications. Dyslipidemia directly correlates with the underlying pathology of nephrotic syndrome and represents a critical factor in managing cardiovascular health in these patients.

While hypertriglyceridemia is a specific form of dyslipidemia that can also indicate increased cardiovascular risk, the broader term "dyslipidemia" encompasses all lipid abnormalities, making it a more comprehensive answer. Hypotension and hypoglycemia are not characteristically associated with nephrotic syndrome in a way that indicates increased

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