Which of the following is NOT a common presentation of Wilson's disease in young adults?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Wilson's disease is a genetic disorder characterized by excessive accumulation of copper in the body, leading to a variety of clinical manifestations. In young adults, the common presentations typically include liver disease, neuropsychiatric symptoms, and abnormal liver function tests due to hepatic dysfunction caused by copper accumulation.

Liver disease manifests as conditions such as hepatitis, cirrhosis, or acute liver failure, while neuropsychiatric symptoms can range from personality changes and mood disorders to more severe manifestations like movement disorders or cognitive decline. Abnormal liver function tests reflect liver damage and dysfunction, which is a hallmark of the disease as the liver is often one of the first organs affected.

In contrast, painful joint swelling is not a typical presentation of Wilson's disease in young adults. While arthralgias and arthritis can occur particularly in those with long-standing disease or copper deposits, it is not a common initial presentation. Joint symptoms would generally not dominate the clinical picture compared to hepatic and neuropsychiatric issues, which are more characteristic in young adults suffering from Wilson's disease. Therefore, painful joint swelling does not align with the usual clinical presentations associated with this condition.

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