Which medication is commonly used for smoking cessation?

Bupropion is commonly used for smoking cessation due to its unique mechanism of action as a norepinephrine-dopamine reuptake inhibitor. It helps to reduce withdrawal symptoms and cravings associated with nicotine addiction, making it an effective option for individuals trying to quit smoking. The medication has been shown to double the chances of successfully quitting compared to placebo and is often chosen for its lower risk of weight gain and absence of nicotine.

Other options such as clonidine, while it can help manage withdrawal symptoms, are not first-line treatments for smoking cessation. Sertraline, an antidepressant, may help with mood disorders but is not specifically indicated for smoking cessation. Dexamethasone, a corticosteroid, does not have any role in smoking cessation and is used primarily for its anti-inflammatory properties. Thus, bupropion stands out as the primary medication for aiding individuals in quitting smoking.