Which lifestyle factor is a significant risk for pancreatic cancer?

A high-fat diet is recognized as a significant risk factor for pancreatic cancer. Research has shown that dietary patterns high in fat, particularly saturated fats, can promote the development of pancreatic cancer through several mechanisms. High-fat diets can lead to obesity, insulin resistance, and alterations in the metabolism of certain nutrients, which may contribute to cancer development. Additionally, unhealthy dietary fat can cause chronic inflammation, which is another known risk factor for various types of cancer, including those of the pancreas.

In contrast, regular exercise, low sugar intake, and high fiber diets are generally associated with a reduced risk of various cancers, including pancreatic cancer. Physical activity helps maintain a healthy weight, improve insulin sensitivity, and reduce inflammation. A low sugar intake can help prevent obesity and metabolic syndrome, which are linked to an increased risk of cancer. Similarly, high fiber diets are protective due to their association with improved gut health, reduced insulin levels, and potentially protective metabolites from fiber fermentation.