Which is NOT a common complication associated with autosomal dominant polycystic kidney disease (ADPKD)?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of multiple cysts in the kidneys, leading to various complications. Hypertension is a well-documented complication, often resulting from renal vascular changes and the effects of cyst growth. Bilateral flank masses can occur due to the enlargement of the kidneys as cysts develop, which gives the kidneys a palpable surface on examination. Additionally, individuals with ADPKD have an increased propensity for developing berry aneurysms due to the underlying genetic factors that also affect the vasculature.

Diabetes insipidus, however, is not a common complication of ADPKD. This condition typically arises from issues related to the production or action of antidiuretic hormone (ADH). While kidney function can be affected in ADPKD, the specific mechanism of diabetes insipidus is not directly related to the cystic changes seen in this disease. Therefore, it does not arise as a significant complication in patients suffering from ADPKD, making it the correct choice for this question.

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