Which features are included in MEN type 2b?

MEN type 2B, or Multiple Endocrine Neoplasia type 2B, is characterized by a specific combination of clinical features. Among these, mucosal neuromas and pheochromocytomas are prominent.

Mucosal neuromas are benign tumors that typically appear on the lips, tongue, and oral mucosa and are often one of the earliest clinical findings in patients with MEN 2B. Pheochromocytomas, which are tumors of the adrenal glands that can secrete catecholamines, lead to episodes of hypertension, palpitations, and diaphoresis. The presence of these tumors is a critical diagnostic criterion for MEN 2B.

Other features commonly associated with MEN 2B include medullary thyroid carcinoma, but the question specifically highlights mucosal neuromas and pheochromocytomas as key identifiers of this syndrome. Therefore, the combination of these two findings aligns perfectly with the profile of MEN type 2B.

The other options present features associated with different syndromes or conditions; for example, adrenal insufficiency and thyroid tumors are more closely related to other types of Multiple Endocrine Neoplasia. Therefore, the correct distinguishing features for MEN type 2B are indeed