What type of crystals are found in pseudogout?

Pseudogout is characterized by the presence of calcium pyrophosphate dihydrate (CPPD) crystals. These crystals are typically rhomboid-shaped and can be seen under polarized light microscopy. The condition is also known as calcium pyrophosphate dihydrate crystal arthritis and often presents with joint pain and swelling, similar to gout, but it differs in the type of crystal that causes the inflammatory process.

Ideally, the presence of rhomboid-shaped CPPD crystals in synovial fluid confirms the diagnosis of pseudogout. This distinguishes it from gout, where monosodium urate crystals are involved, and serves as a key differentiating factor in clinical practice. Understanding the morphology of these crystals and their implications in joint pathology is essential for accurate diagnosis and management of crystal-induced arthropathies.