What is the typical presentation of dermatitis herpetiformis?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Dermatitis herpetiformis typically presents as a papulovesicular rash, which consists of small, itchy blisters and raised red bumps. This condition is associated with celiac disease and is characterized by a symmetric distribution, commonly affecting the elbows, knees, buttocks, and scalp. The blistering lesions are often intensely pruritic and can be mistaken for other skin conditions, but the papulovesicular nature and their appearance on extensor surfaces are key distinguishing features.

The rash tends to resolve with a gluten-free diet, as it is closely linked to the ingestion of gluten in susceptible individuals. The involvement of small vesicles and papules, often grouped together, contributes to the characteristic presentation that defines dermatitis herpetiformis.

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