What is the most common nephritic syndrome in adults?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

IgA nephropathy, also known as Berger's disease, is recognized as the most prevalent nephritic syndrome in adults. It arises from the deposition of IgA antibodies in the mesangial cells of the glomeruli, leading to inflammation and kidney damage. This condition commonly presents with episodes of hematuria (blood in urine), often associated with upper respiratory infections, as well as possible proteinuria.

The onset of IgA nephropathy typically occurs in younger adults and can lead to progressive kidney dysfunction over time, though many patients can remain stable for years. Diagnosis often involves the presence of IgA deposits in the kidney tissue, which can be confirmed through a renal biopsy if needed.

In contrast, while minimal change disease is the most common nephrotic syndrome in children and can occur in adults, it is not the most common nephritic syndrome overall. Post-streptococcal glomerulonephritis is usually seen in children following a streptococcal infection, making it less common in adults. Membranous nephropathy, though significant in adult populations, occurs less frequently than IgA nephropathy and is associated more often with nephrotic syndrome rather than nephritic syndrome. Therefore, IgA neph

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