What is the most common type of thyroid cancer that also has the best prognosis?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Papillary thyroid carcinoma is the most common type of thyroid cancer, accounting for approximately 80% of all thyroid cancer cases. It typically arises from the follicular cells of the thyroid gland and is characterized by its unique histological features, such as papillary structures and nuclear grooves.

One of the reasons papillary thyroid carcinoma has the best prognosis among thyroid cancers is its generally indolent behavior. Most patients diagnosed with this type of cancer are relatively young and often present with small tumors that are either asymptomatic or have minimal symptoms. The cancer tends to spread slowly, and many cases are confined to the thyroid itself at the time of diagnosis.

Furthermore, the overall survival rate for papillary thyroid carcinoma is quite high, often exceeding 90% for patients diagnosed, especially when the cancer is detected at an early stage. Treatment typically includes surgical removal of the thyroid (thyroidectomy) and may involve radioactive iodine therapy to eradicate any remnants of cancerous tissue.

In contrast, follicular thyroid carcinoma, although more aggressive than papillary carcinoma, still tends to have a favorable prognosis but is not as common. Medullary thyroid carcinoma originates from parafollicular cells (C cells) and tends to have a poorer prognosis compared to papillary carcinoma. An

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