What is the condition characterized by umbilicated vesicles over areas of eczema due to primary HSV infection?

The condition characterized by umbilicated vesicles over areas of eczema due to primary HSV infection is eczema herpeticum. This occurs when the herpes simplex virus (HSV) infects an area of the skin that is already affected by atopic dermatitis (eczema). The presence of existing eczema creates a favorable environment for the virus, leading to the development of vesicular lesions that may be umbilicated (having a depressed center).

In eczema herpeticum, the vesicles may become confluent and can be painful, leading to potential complications such as secondary bacterial infections. This condition can be particularly concerning in patients with a history of atopic dermatitis because their skin barrier is compromised, increasing the risk of viral widespread dissemination.

Other conditions mentioned do not fit the described scenario. Shingles, caused by varicella-zoster virus, presents with a dermatomal rash but does not typically occur over eczema or present as umbilicated vesicles. Herpes gladiatorum refers to HSV infections occurring on the skin, often in wrestlers, usually located on the face or neck, not in areas affected by eczema. Varicella, or chickenpox, presents with a generalized vesicular rash, but it does not specifically relate to pre-existing eczema