What is a common electrolyte imbalance seen in Addison's disease?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Addison's disease, or primary adrenal insufficiency, typically leads to a deficiency in the production of adrenal hormones, particularly cortisol and aldosterone. One of the hallmark features of this condition is an imbalance in electrolytes, primarily affecting sodium and potassium levels.

In Addison's disease, the lack of aldosterone results in decreased reabsorption of sodium in the kidneys and increased excretion of potassium. This state creates a scenario where potassium levels can become elevated, leading to hyperkalemia. The high potassium levels can cause various complications, including cardiac arrhythmias.

Additionally, since aldosterone normally promotes sodium retention, its deficiency contributes to hyponatremia or low sodium levels. This combination of low sodium and high potassium is classic in Addison's disease, making high potassium the correct answer in this context. Understanding these electrolyte imbalances is crucial for diagnosing and managing patients with Addison's disease effectively.

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