What is a common complication associated with Chagas disease?

Chagas disease, caused by the parasite Trypanosoma cruzi, is associated with several long-term complications, with myocarditis being one of the most significant. Myocarditis in Chagas disease occurs due to the direct invasion of cardiac tissue by the parasite, leading to inflammation and damage. Over time, this can progress to chronic cardiomyopathy, arrhythmias, and heart failure.

The pathophysiology underlying myocarditis in Chagas disease involves both direct parasitic effects and immune-mediated damage. Patients may present with symptoms ranging from asymptomatic to chest pain, palpitations, or signs of heart failure. Diagnosis of the cardiac complications often involves electrocardiograms and imaging studies, which may reveal structural and functional changes in the heart.

In contrast, the other options presented do not have a significant relationship with Chagas disease. While glomerulonephritis, rheumatic fever, and acute kidney injury can be associated with other infectious conditions or systemic diseases, they are not common complications of Chagas disease. Thus, myocarditis stands out as the key complication in the context of this parasitic infection.