What is a common clinical finding in congenital syphilis?

In congenital syphilis, a common clinical finding is hepatosplenomegaly. This condition results from the systemic involvement of the infection, particularly during the second trimester of pregnancy when the fetus is most susceptible. The mother can transmit Treponema pallidum, the causative agent of syphilis, to the fetus, leading to a range of complications. Hepatosplenomegaly occurs due to the inflammatory response in the liver and spleen, which can become enlarged as the body attempts to fight the infection.

Other presentations of congenital syphilis can include skeletal abnormalities, skin rashes, and inflammatory responses in various organs, but hepatosplenomegaly is notably prevalent. It's essential to recognize this finding as part of the broader clinical picture of congenital syphilis, which can lead to significant morbidity if not treated appropriately.