What condition is indicated by migratory thrombophlebitis?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Migratory thrombophlebitis, characterized by recurrent episodes of superficial vein inflammation and thrombosis that appear in different locations over time, is classically associated with Trousseau's syndrome. This syndrome is often a paraneoplastic phenomenon linked to malignancies, particularly adenocarcinomas such as pancreatic cancer.

The underlying mechanism involves the hypercoagulable state induced by the tumor, which releases pro-coagulative factors into the circulation. This hypercoagulability can lead to venous thrombosis in multiple sites, hence the term "migratory." Recognizing this condition is crucial as it can serve as a warning sign of an underlying malignancy, prompting further investigation in a patient who exhibits this symptom.

Other conditions listed, such as viral infections and thromboembolism, do not typically present with the migratory pattern of thrombophlebitis that is characteristic of Trousseau's syndrome. Trauma, while it can lead to localized thrombophlebitis, is not associated with the migratory nature linked to malignancy. Therefore, Trousseau's syndrome is the most appropriate choice reflecting the condition indicated by migratory thrombophlebitis.

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