What class of drug is phenelzine?

Phenelzine belongs to the class of drugs known as monoamine oxidase inhibitors (MAOIs). MAOIs function by inhibiting the enzyme monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By preventing the degradation of these neurotransmitters, phenelzine enhances their availability, which can lead to improved mood and alleviation of depressive symptoms.

MAOIs are particularly used in treating various mood disorders, especially in patients who have not responded to other treatments. They are noted for their efficacy but also come with dietary restrictions and potential drug interactions due to the risk of hypertensive crises when consuming certain tyramine-rich foods or interacting with other medications.

Since phenelzine does not fall under the categories of selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), or serotonin-norepinephrine reuptake inhibitors (SNRIs), the classification as a monoamine oxidase inhibitor is correct and highlights its unique mechanism of action among antidepressants.