What characteristic CT finding is associated with Huntington's disease?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Huntington's disease is characterized by the atrophy of specific brain regions, particularly the caudate nuclei, which are part of the basal ganglia. As the caudate nuclei degenerate, there is resultant enlargement of the lateral ventricles. This finding can be visualized on a CT scan, where the ventricles appear larger than normal due to the loss of surrounding brain tissue.

The process of degeneration in Huntington's disease leads to a reduction in the volume of the affected areas, and as these structures shrink, the spaces that were previously occupied by them, such as the lateral ventricles, become relatively larger. This lateral ventricular enlargement is a classic radiological finding in patients with Huntington's disease and corresponds with the clinical manifestations of movement disorders and cognitive decline typical of the condition.

The other options provided do not reflect the primary CT findings associated with Huntington’s disease. While cerebellar atrophy and atrophy of the temporal lobe can occur in different neurological disorders, they are not characteristic of Huntington's disease. Increased intracranial pressure is not a common finding associated with this condition either, as the disease typically involves tissue loss rather than swelling.

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