What are the primary symptoms of a beta-blocker overdose?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

In a beta-blocker overdose, the primary symptoms are indeed AV block, bradycardia, and hypotension. Beta-blockers work by blocking adrenergic receptors, which leads to a decrease in heart rate and myocardial contractility. This blockade can result in conduction disturbances such as atrioventricular (AV) block, often presenting as bradycardia, which is a slowed heart rate commonly observed in overdose situations. Hypotension arises due to the decreased cardiac output and reduced sympathetic tone, causing inadequate perfusion and potential shock.

Patients may also exhibit other signs, such as dizziness or syncope, but the hallmark features are the combined effects of bradycardia and hypotension due to the excessive blockade of beta-adrenergic receptors. Recognizing these symptoms is crucial for timely management, which may include supportive care and the use of medications such as atropine or glucagon.

The incorrect options reflect symptoms of entirely different medical conditions or drug overdoses, highlighting the importance of accurate diagnosis in clinical scenarios.

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