What are the main features of a hydatidiform mole?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

A hydatidiform mole, also known as a molar pregnancy, is characterized by the abnormal proliferation of trophoblastic tissue, which leads to distinct clinical findings. The correct choice highlights three primary features:

  1. Large Uterus: In a hydatidiform mole, the uterus often expands significantly due to the abnormal growth of the placental tissue. This enlargement can be much greater than what would be expected for the gestational age, which is a key feature clinicians look for when diagnosing this condition.
  1. Hyperemesis: Many patients with a hydatidiform mole experience severe nausea and vomiting, a condition referred to as hyperemesis gravidarum. This is thought to be related to elevated levels of human chorionic gonadotropin (HCG) produced by the abnormal trophoblastic tissue.

  2. High HCG Levels: The serum levels of HCG in cases of hydatidiform mole are typically much higher than those seen in a normal pregnancy. This elevated HCG can lead to additional symptoms and complications, making it a diagnostic marker often used in conjunction with ultrasound.

These features serve as critical indicators for healthcare providers when assessing a patient for a possible molar pregnancy, guiding them toward a correct

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