What are the first signs of magnesium toxicity during eclampsia treatment?

Magnesium toxicity can occur when treating eclampsia, particularly if magnesium sulfate is administered in excessive amounts. The initial signs of magnesium toxicity are often neurological and include hyporeflexia, which is characterized by decreased or absent reflexes. This occurs because magnesium acts as a central nervous system depressant, affecting neuromuscular function.

As magnesium levels rise, the first observable sign is typically a reduction in reflexes, particularly the deep tendon reflexes. Clinicians monitor reflexes closely in patients receiving magnesium to catch any signs of toxicity early.

While seizures can occur in cases of magnesium toxicity, they are not usually the first signs. Similarly, hypertension and altered mental status may indicate more severe toxicity but are generally not the initial manifestations. Recognizing hyporeflexia as an early sign is critical for timely intervention to prevent further complications associated with magnesium toxicity in patients being treated for eclampsia.