In bacterial vaginosis, what type of cells are commonly identified on wet mount?

Study for the USMLE Step 2 CK Exam. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

In bacterial vaginosis, the presence of clue cells is a key feature observed during a wet mount examination. Clue cells are vaginal epithelial cells that have a stippled appearance due to the presence of bacterial overgrowth, which obscures the cell's borders. This morphological change occurs because of the alteration of the normal vaginal flora, where there is an overgrowth of anaerobic bacteria, displacing the usual lactobacilli.

The identification of clue cells is significant because it helps differentiate bacterial vaginosis from other conditions such as vulvovaginal candidiasis and trichomoniasis. Their presence, along with a fishy odor and a homogeneous vaginal discharge, contributes to the clinical diagnosis of this condition.

Other cell types that may be observed, such as leukocytes or vaginal epithelial cells, do not provide the same diagnostic specificity for bacterial vaginosis. Endometrial cells are not typically relevant in the context of a wet mount for vaginal infections, making clue cells the correct answer in this scenario.

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