Amiodarone use is contraindicated in patients with which of the following conditions?

Amiodarone is a class III antiarrhythmic medication commonly used for the treatment of various types of arrhythmias. However, its use can be contraindicated in certain conditions due to the risk of exacerbating existing health problems or causing severe side effects.

In the case of chronic lung disease, amiodarone carries a significant risk of inducing pulmonary toxicity—a severe adverse effect that can manifest as pulmonary fibrosis or pneumonitis. Patients with chronic lung disease are particularly vulnerable to these effects, as their lung function may already be compromised. Therefore, the risk associated with using amiodarone in this population outweighs the potential benefits, making it contraindicated.

In contrast, hypertension, heart failure, and diabetes do not present the same level of risk for developing life-threatening side effects as those seen with chronic lung disease when considering amiodarone use. While caution and monitoring may be required in patients with heart failure due to the drug’s potential to adversely affect cardiac function, and in diabetic patients due to possible metabolic changes, these conditions are not absolute contraindications like chronic lung disease is.